a wheelgun cleaning/shooting tale ...
i'd been using LVL (lehigh valley lube) for cleaning out a number of different kinds of guns, from flintlocks to centerfire to rimfire. i load my ruger sp101 .357mag rounds with tumble lubed 158 grain cast bullets. the tumble lube is white label 45-45-10, very sparsely used, with just enuf to fully thin coat the lead.
after cleaning/lubing this new and unfired revolver only with LVL, i loaded 100 cartridges with a light load of w231 in starline brass and proceeded to shake down the pistol. after 5 cylinders worth of firings, i sensed a stiffness to the wheel - it felt like something was binding it from turning. then feeding the rounds into the cylinder became tight and "sticky". it got to the point where it wasn't at all easy to load and shoot, and that range experience ended abruptly.
a subsequent very thorough cleaning/lubing with breakfree restored the cylinder to spinning freely, tumble lubed cartridges loaded and fired easily, and the trigger/hammer worked well.
clearly, the LVL had reacted with the tumble lube in a not-so-good manner. this is not at all to say that LVL is in any manner "bad" - i still use it for guns that don't load with tumble lubed bullets. point taken and remembered.