Don't lose your grip...frame
Ready,
I bought a new Ruger Blackhawk, .45 Colt, 7.5". Shot it for about 2 years. Shot everything from light to heavy. The aluminum grip frame broke during a box of 23 gr h4227 under Lee 300 gr RF at about 1250 fps. That was maybe the third box of those heavy hitters. Ruger told me that was fairly common with heavy .45s and the aluminum frame. They wanted $225 to put a steel one on and blue it. I wound up getting a brass one from a gentleman on this forum and got back in business. The brass looks nice. But be ye informed. If your grip frame is aluminum, start looking for what's going to replace it, or leave the 300 grs on the shelf.